The exception to the rule is the DOT1 household, members of which methylate K79 lawyers in my area the globular region of histone H3 and that are structurally not associated to SET-area proteins 4 - 6 Latest work means that SET-area-containing proteins methylate a number of proteins in addition to histones (see later); they need to due to this fact be named protein lysine methyltransferases reasonably than histone lysine methyltransferases.

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